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Horizon Europe Project

SafeDrop

Multimodal Photonic-Electronic Sensor Platform for Rapid Health and Environmental Diagnostics

Bio-inspired canine olfaction MZI + TFT K-cells ppb-level detection

Laboratory-grade chemical detection, anywhere — in minutes, not days. A bio-inspired "digital dog nose" emulating mammalian olfaction for real-time, on-site diagnostics.

48
Months
10
Partners
7
Countries
4
Demonstrators
TRL 3→5
Demonstrator maturity
(photonic techniques to TRL 7)
Jun 2026
Project start
What our consortium aims to do

The aim of the SafeDrop project

SafeDrop aims to raise the maturity of a bio-inspired, multimodal photonic–electronic sensor platform from proof-of-concept to field-validated demonstrators — delivering laboratory-grade chemical fingerprints on-site, in minutes rather than days.

By fusing silicon-photonic Mach–Zehnder interferometers with thin-film transistors in co-localised K-cells, and decoding the resulting fingerprints with AI/MIMO analytics, SafeDrop will strengthen Europe's strategic autonomy in advanced sensor technologies while enabling faster, more confident decisions in water, health, food and air.

Explore the project plan

"Like a dog's nose, SafeDrop does not rely on a single perfect sensor — it learns from a constellation of imperfect, cross-responsive channels to recognise what matters in the field."

>99%
Target classification accuracy
Minutes
On-site time to result
General information about the project

Why it matters

Laboratory analysis is accurate but slow, centralised and expensive. Portable field sensors are fast, but often lack the selectivity to be trusted for critical decisions.

SafeDrop bridges this gap: a compact, field-deployable platform that delivers laboratory-grade, multimodal chemical fingerprints on-site — turning days of waiting into minutes of actionable insight.

Days
Typical lab turnaround today
Minutes
SafeDrop on-site target
< 1 ppb (Pb)
< 100 CFU/mL (pathogens)

Fast and selective. By fusing optical and electrical readouts and decoding them with machine learning, SafeDrop targets both the speed of field sensors and the confidence of the lab.

We are committed to make an impact

In SafeDrop we will

Six objectives guiding the consortium from platform integration to open-ecosystem release.

01

Integrate photonics & electronics

Co-localise MZI sensors and TFT channels into a scalable 32-cell K-cell array on a CMOS-compatible process.

02

Build a cross-responsive coating library

Deposit >20 partially overlapping organic-semiconductor coatings via ESJET printing for rich chemical fingerprints.

03

Decode with AI / MIMO

Fuse optical and electrical channels to classify targets with high accuracy and low false-positive rates.

04

Validate four demonstrators

Field-test across water quality, point-of-care health, food safety and airborne VOC / drone sensing.

05

Drive down cost & power

Target a disposable cartridge ≤ €10 (≤ €5 at scale) and a <1 W system power budget for field deployment.

06

Open the ecosystem

Release open PDKs, open hardware and standards contributions to grow a wider European sensor community.

How it works

From sample to answer

A single, synchronous pipeline turns a raw sample into an actionable result.

SafeDrop pipeline: sample intake, K-cell array, dual readout and AI fingerprint decoding
Technology pillars

Five technologies, one platform

A digital dog nose built on photonics, electronics, printing, microfluidics and AI.

MZI photonics

Evanescent-field Mach–Zehnder interferometers with thermo-optic multiplexing.

TFT electronics

Co-localised thin-film transistors adding orthogonal selectivity via ΔIDS.

ESJET coatings

Precision deposition of >20 overlapping organic-semiconductor coatings.

Microfluidics

Pump-free sample delivery in a low-cost, disposable cartridge.

The SafeDrop compact, pump-free microfluidic system, based on FBK's advanced Electrowetting-on-Dielectric (EWOD) technology, addresses the project targets for portable, cost-effective alternatives to traditional testing equipment. Traditional microfluidics rely on complex, rigid networks of pumps and channels that limit flexibility and field use. SafeDrop replaces these bulky components with a low-power, highly scalable droplet-management system. By applying precise electrical signals to an electrode array, the platform dynamically modulates droplet contact angles, routing liquid samples across integrated sensors with high accuracy.

By merging low-power operation with simple manufacturing, the SafeDrop microfluidic module delivers a versatile, highly integrated solution designed to meet the strict demands of next-generation diagnostic and environmental monitoring tools.

The key advantages for the SafeDrop project are:

  • Enhanced portability: eliminates mechanical micropumps for a lightweight, compact integrated system
  • On-site detection: sample management to analyse multiple contaminants, biomarkers, and metabolites on site
  • Flexible and scalable: reconfigurable droplet routing tailored to diverse testing needs

AI / MIMO analytics

>99% classification accuracy and >95% false-positive reduction.

Project targets

Ambitious, measurable targets

These are project targets and remain so until validated through the demonstrators.

TRL 3→5 demonstrators
TRL 7 for core photonic techniques
<1 W
System power budget
≤ €10
Cartridge (≤ €5 at scale)
>99%
Target classification accuracy
A group of experienced professionals

SafeDrop consortium

10 leading European organisations from 7 countries — research institutes, universities and industry working together.

Fraunhofer IAP
Fraunhofer IAP
Coordinator • Germany
ICMPP
ICMPP Petru Poni
Romania
FBK
Fondazione Bruno Kessler
Italy
PHIX
PHIX BV
Netherlands
DCU
Dublin City University
Ireland
MTU
Munster Technological University
Ireland
Flowphys
Flowphys AS
Norway
Oliveris Tech
Oliveris Tech Incubator
Ireland
Lancaster University
Lancaster University
United Kingdom
Spike Renewables
Spike Renewables
Italy

Let's collaborate

For press, collaboration, or open-ecosystem inquiries, reach out to the coordinator or subscribe to receive news, results and resources throughout SafeDrop's lifetime.

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